Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713573 | 0.79 | MAOA (0.55) | BCL2MCL1MEN1KMT2AMAOA | |
| SCHEMBL9713712 | 0.78 | DDAH1 (0.41) | PDE7ABCL2MCL1MAOAMAOB | |
| SCHEMBL9713415 | 0.77 | BCL2 (0.39) | PDE7ABCL2MCL1MAPTHPGD | |
| SCHEMBL9713222 | 0.76 | PTPN1 (0.38) | L3MBTL1POLBMAPTMEN1KMT2A | |
| SCHEMBL9713334 | 0.73 | MCL1 (0.57) | BCL2MCL1MAOAMAOB | |
| SCHEMBL9713331 | 0.73 | SLC6A4 (0.39) | L3MBTL1BCL2MCL1MAPTSMN1; SMN2 | |
| SCHEMBL9713721 | 0.70 | P4HB (0.44) | L3MBTL1BCL2MCL1MEN1KMT2A | |
| SCHEMBL9642920 | 0.70 | PTPN1 (0.41) | L3MBTL1POLBBCL2MCL1MAPT | |
| SCHEMBL4682214 | 0.69 | L3MBTL1 (0.96) | L3MBTL1PDE7APOLBMAPTMEN1 | |
| SCHEMBL8773066 | 0.69 | S100A4 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |