Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717374 | 0.81 | NFE2L2 (0.40) | NFE2L2HSD11B1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL9715765 | 0.80 | PTGS2 (0.40) | PTGS1PTGS2KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL9715714 | 0.79 | ALDH1A1 (0.47) | PTGS1PTGS2KMT2ASMN1; SMN2HTT | |
| SCHEMBL9715754 | 0.78 | PTGS1 (0.52) | PTGS1PTGS2KMT2ANPC1RAB9A | |
| SCHEMBL9715755 | 0.78 | PTGS2 (0.44) | PTGS1PTGS2KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9632497 | 0.77 | PTGS2 (0.47) | PTGS1PTGS2KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6547421 | 0.77 | MAPK14 (0.44) | NFE2L2HSD11B1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL9715718 | 0.77 | CXCL8 (0.41) | PTGS1PTGS2AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL9715759 | 0.75 | TSHR (0.45) | PTGS1PTGS2KMT2ALMNAALDH1A1 | |
| SCHEMBL6547363 | 0.74 | TDP1 (0.48) | NFE2L2HSD11B1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304495-B1 | PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-4908473-A | Reacting a (1-arylethenyl)vinylbenzene with carbon monoxide and water or alcohol in the presence of carbonylation catalyst | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-03-13 | — | — | US | disclosed |