Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724808 | 0.85 | MEN1 (0.53) | RAB9ANPC1HTTCYP2D6ALDH1A1 | |
| SCHEMBL9724833 | 0.84 | LMNA (0.54) | PKMRAB9ANPC1HTTCYP3A4 | |
| SCHEMBL26502092 | 0.83 | PKM (0.65) | PKMRAB9ANPC1HTTNAMPT | |
| SCHEMBL9586701 | 0.82 | PKM (0.57) | PKMRAB9ANPC1HTTNAMPT | |
| SCHEMBL9724784 | 0.81 | PKM (0.62) | PKMRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL9724829 | 0.77 | BACE1 (0.54) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18439983 | 0.76 | RAB9A (0.61) | PKMRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL9724970 | 0.76 | MAPT (0.55) | RAB9ANPC1CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL9724967 | 0.76 | MAPT (0.67) | RAB9ANPC1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16008987 | 0.76 | FPR2 (0.62) | PKMRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |