Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724808 | 0.85 | MEN1 (0.53) | MAPTTP53ALDH1A1RAB9AGAA | |
| SCHEMBL9724970 | 0.84 | MAPT (0.55) | MAPTTP53ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL9724967 | 0.84 | MAPT (0.67) | MAPTTP53ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL9724923 | 0.84 | RAB9A (0.50) | HDAC1MAPTTP53SMN1; SMN2RAB9A | |
| SCHEMBL9724979 | 0.81 | MME (0.53) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9724859 | 0.80 | ALDH1A1 (0.60) | MAPTTP53ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9724920 | 0.80 | RAB9A (0.67) | MAPTALDH1A1RAB9AMEN1LMNA | |
| SCHEMBL9724829 | 0.77 | BACE1 (0.54) | MAPTTP53SMN1; SMN2RAB9AGAA | |
| SCHEMBL9724833 | 0.75 | LMNA (0.54) | ALDH1A1SMN1; SMN2RAB9AMEN1LMNA | |
| SCHEMBL9724796 | 0.75 | HDAC1 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |