Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724959 | 0.83 | GAA (0.55) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9724796 | 0.82 | HDAC1 (0.52) | NPC1RAB9APOLBMAPK1 | |
| SCHEMBL28279152 | 0.82 | ROCK2 (0.57) | KCNQ2ALDH1A1GPR55IDO1CASR | |
| SCHEMBL7282286 | 0.79 | MME (0.57) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL9724808 | 0.79 | MEN1 (0.53) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9724978 | 0.79 | KMT2A (0.52) | ALDH1A1GPR55IDO1MEN1KMT2A | |
| SCHEMBL9724825 | 0.78 | TSHR (0.55) | ALDH1A1IDO1MEN1KMT2ANPC1 | |
| SCHEMBL6205051 | 0.78 | ALDH1A1 (0.63) | KCNQ2ALDH1A1GPR55IDO1CASR | |
| SCHEMBL6374921 | 0.77 | FPR2 (0.67) | ALDH1A1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL6374913 | 0.77 | FPR2 (0.67) | ALDH1A1MEN1KMT2ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |