Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728456 | 0.77 | TDP1 (0.35) | ADRA2AADRA2BADRA2CKMT2AMEN1 | |
| SCHEMBL9728352 | 0.70 | SMN1; SMN2 (0.40) | MAPTTSHRALDH1A1LMNA | |
| Levodropropizine SCHEMBL29043 | 0.69 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CKMT2AMEN1 | |
| Dropropizine SCHEMBL93975 | 0.69 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CKMT2AMEN1 | |
| Dropropizine SCHEMBL8379428 | 0.69 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CKMT2AMEN1 | |
| Dropropizine SCHEMBL27495915 | 0.68 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CKMT2AMEN1 | |
| SCHEMBL574986 | 0.68 | NPSR1 (0.38) | KMT2AMEN1MAPTTSHRMAPK1 | |
| SCHEMBL9728419 | 0.68 | L3MBTL1 (0.43) | KMT2AMAPTTSHRL3MBTL1ALDH1A1 | |
| Dropropizine SCHEMBL10445730 | 0.63 | ADRA2A (0.83) | ADRA2AADRA2BADRA2CKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1585091 | 0.63 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098926-A | Antitumor agents | UNIVERSITY PATENTS, INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-4888341-A | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-12-19 | — | — | US | disclosed |