Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171966 | 0.70 | GFER (0.59) | L3MBTL1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9728352 | 0.69 | SMN1; SMN2 (0.40) | ALDH1A1MAPTKDM4ELMNAHTT | |
| SCHEMBL9728456 | 0.68 | TDP1 (0.35) | L3MBTL1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL574986 | 0.67 | NPSR1 (0.38) | ALDH1A1MAPTKDM4ELMNAHTT | |
| SCHEMBL7553199 | 0.64 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL9728417 | 0.61 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1MAPTNPSR1KMT2A | |
| SCHEMBL13740362 | 0.61 | HDAC3 (0.41) | L3MBTL1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL17157069 | 0.59 | SMN1; SMN2 (0.55) | ALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL6695193 | 0.58 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4ELMNAHTT | |
| SCHEMBL31670698 | 0.58 | SIGMAR1 (0.55) | ALDH1A1MAPTKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098926-A | Antitumor agents | UNIVERSITY PATENTS, INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-4888341-A | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-12-19 | — | — | US | disclosed |