Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CAD | P27708 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186588 | 0.80 | CHRNB2 (0.35) | CA1CA2CADCYP1A2TSHR | |
| SCHEMBL16737814 | 0.80 | DNM1 (0.39) | LMNA | |
| Hydrochloric Acid SCHEMBL28335915 | 0.78 | LMNA (0.36) | CA1CA2CADCYP1A2TSHR | |
| SCHEMBL9700328 | 0.77 | PGR (0.32) | FDPS | |
| SCHEMBL27523663 | 0.76 | CAD (0.35) | CADFDPS | |
| SCHEMBL3280973 | 0.74 | TGFBR1 (0.43) | — | |
| SCHEMBL3285064 | 0.74 | TSHR (0.47) | TSHR | |
| Hydrochloric Acid SCHEMBL29162350 | 0.72 | TGFBR1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL29008141 | 0.72 | TSHR (0.45) | TSHR | |
| SCHEMBL7401448 | 0.71 | KMT2A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4253442-B1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | EVONIK OPERATIONS GMBH (DE) | 2026-04-29 | — | — | EP | claimed |
| US-12540224-B2 | Process and composition for the production of flexible polyurethane foam | EVONIK OPERATIONS GMBH (DE) | 2026-02-03 | — | — | US | claimed |
| US-20260028445-A1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | EVONIK OPERATIONS GMBH (DE) | 2026-01-29 | — | — | US | claimed |
| EP-4562069-A1 | TERTIARY AMINO-AMIDE COMPOSITION USEFUL IN MAKING POLYURETHANE POLYMERS | Evonik Operations GmbH (DE) | 2025-06-04 | — | — | EP | claimed |
| EP-4562070-A1 | METHOD FOR PREPARING FLEXIBLE SLABSTOCK POLYURETHANE FOAM | Evonik Operations GmbH (DE) | 2025-06-04 | — | — | EP | claimed |
| CN-119630722-A | Tertiary amino-amide compositions useful in the manufacture of polyurethane polymers | 赢创运营有限公司 | 2025-03-14 | — | — | CN | claimed |
| EP-3481878-B1 | AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM | EVONIK OPERATIONS GMBH (DE) | 2024-05-22 | — | — | EP | claimed |
| WO-2024022833-A1 | METHOD FOR PREPARING FLEXIBLE SLABSTOCK POLYURETHANE FOAM | EVONIK OPERATIONS GMBH (DE) | 2024-02-01 | — | — | WO | claimed |
| WO-2024022832-A1 | TERTIARY AMINO-AMIDE COMPOSITION USEFUL IN MAKING POLYURETHANE POLYMERS | EVONIK OPERATIONS GMBH (DE) | 2024-02-01 | — | — | WO | claimed |
| EP-4253442-A2 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | Evonik Operations GmbH (DE) | 2023-10-04 | — | — | EP | claimed |
| EP-3954722-A1 | PROCESS AND COMPOSITION FOR THE PRODUCTION OF FLEXIBLE POLYURETHANE FOAM | Evonik Operations GmbH (DE) | 2022-02-16 | — | — | EP | claimed |
| EP-3931177-A1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | Evonik Operations GmbH (DE) | 2022-01-05 | — | — | EP | claimed |
| CN-113544115-A | Amine compositions useful for preparing stable polyurethane foam systems | 赢创运营有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-107922564-B | Trimerization catalysts from sterically hindered salts and tertiary amines having isocyanate-reactive groups | 赢创运营有限公司 | 2021-10-19 | — | — | CN | claimed |
| US-11021561-B2 | Amine composition useful for making polyurethane foam | EVONIK OPERATIONS GMBH (DE) | 2021-06-01 | — | — | US | claimed |
| US-10759892-B2 | Trimerization catalysts from sterically hindered salts and tertiary amines having isocyanate reactive groups | EVONIK OPERATIONS GMBH (DE) | 2020-09-01 | — | — | US | claimed |
| WO-2020018087-A1 | POLYURETHANE FOAM ADDITIVES TO IMPROVE FOAM ADHESION TO ORGANIC POLYMERS | EVONIK DEGUSSA GMBH (DE) | 2020-01-23 | — | — | WO | claimed |
| EP-3481878-A1 | AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM | Evonik Degussa GmbH (DE) | 2019-05-15 | — | — | EP | claimed |
| WO-2018013590-A1 | AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM | EVONIK DEGUSSA GMBH (DE) | 2018-01-18 | — | — | WO | claimed |
| US-20180009930-A1 | AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM | EVONIK OPERATIONS GMBH (DE) | 2018-01-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540224-B2 | Process and composition for the production of flexible polyurethane foam | INTS9, PUF60, INTS6 | CA1 4157/4885CA2 4811/4885CAD 1150/4885 |
| US-20260028445-A1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | RFC2, RFC3, PUF60 | CA1 1294/4885CA2 1772/4885CAD 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.