Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729998 | 0.79 | HDAC3 (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL21310453 | 0.75 | LIPG (0.34) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7506619 | 0.74 | APAF1 (0.40) | HPGDAPAF1CYP2D6CYP2C19FOLH1 | |
| SCHEMBL4189531 | 0.74 | MEN1 (0.44) | APAF1CYP2D6CYP2C19FOLH1NAALAD2 | |
| SCHEMBL468822 | 0.73 | MTNR1A (0.44) | APAF1CYP2D6CYP2C19FOLH1NAALAD2 | |
| SCHEMBL15474169 | 0.73 | APAF1 (0.37) | APAF1CYP2D6CYP2C19FOLH1NAALAD2 | |
| SCHEMBL9730277 | 0.73 | ALDH1A1 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27761217 | 0.72 | CYP2D6 (0.43) | HPGDAPAF1CYP2D6CYP2C19GABRR1 | |
| SCHEMBL18197258 | 0.72 | APAF1 (0.43) | MMEAPAF1ACECYP2D6CYP2C19 | |
| SCHEMBL14110253 | 0.71 | MCL1 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210239704-A1 | ANALOGS AND CONJUGATES OF BETA-AMINOISOBUTYRIC ACID (BAIB) | IDEXX LABORATORIES, INC. | 2021-08-05 | — | — | US | disclosed |
| US-20180120326-A1 | METHODS FOR DETECTING RENAL DISEASE | IDEXX LABORATORIES, INC. | 2018-05-03 | — | — | US | disclosed |
| WO-2016176691-A1 | METHODS FOR DETECTING RENAL DISEASE | IDEXX LABORATORIES, INC. (US) | 2016-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210239704-A1 | ANALOGS AND CONJUGATES OF BETA-AMINOISOBUTYRIC ACID (BAIB) | GABRB1, GABRB2, GABRB3 | HDAC3 1845/4885HDAC4 1647/4885HDAC1 2785/4885 |
| US-20180120326-A1 | METHODS FOR DETECTING RENAL DISEASE | ABAT, SLC1A5, DAO | HDAC3 2962/4885HDAC4 3352/4885HDAC1 3118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.