Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734017 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1SMN1; SMN2HIF1A | |
| SCHEMBL9734163 | 0.75 | HIF1A (0.48) | ALDH1A1KMT2AMEN1HIF1AMAPT | |
| SCHEMBL9734943 | 0.73 | HIF1A (0.44) | ALDH1A1KMT2AMEN1SMN1; SMN2HIF1A | |
| SCHEMBL9733469 | 0.72 | MAPT (0.44) | ALDH1A1KMT2AMEN1HIF1AMAPT | |
| SCHEMBL9738194 | 0.69 | KMT2A (0.42) | ALDH1A1KMT2AMEN1SMN1; SMN2HIF1A | |
| SCHEMBL9737918 | 0.69 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2HIF1AMAPTKDM4E | |
| SCHEMBL9733292 | 0.68 | MEN1 (0.45) | ALDH1A1KMT2AMEN1SMN1; SMN2HIF1A | |
| SCHEMBL9733574 | 0.68 | KMT2A (0.45) | ALDH1A1KMT2AMEN1SMN1; SMN2HIF1A | |
| SCHEMBL15798247 | 0.67 | KMT2A (0.86) | ALDH1A1KMT2AMEN1SMN1; SMN2HIF1A | |
| SCHEMBL9733634 | 0.66 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |