Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734017 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HIF1ASMN1; SMN2PKMKDM4E | |
| SCHEMBL9733634 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HIF1ASMN1; SMN2LMNAPKM | |
| SCHEMBL9734163 | 0.73 | HIF1A (0.48) | ALDH1A1HIF1ATSHRMAPTTP53 | |
| SCHEMBL9733292 | 0.73 | MEN1 (0.45) | ALDH1A1HIF1ASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL9733574 | 0.73 | KMT2A (0.45) | ALDH1A1HIF1ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL9734943 | 0.71 | HIF1A (0.44) | ALDH1A1HIF1ASMN1; SMN2MAPT | |
| SCHEMBL9734030 | 0.71 | ALDH1A1 (0.36) | ALDH1A1PKMRAB9AMAPT | |
| SCHEMBL9733469 | 0.71 | MAPT (0.44) | ALDH1A1HIF1ALMNAPKMKDM4E | |
| SCHEMBL9733819 | 0.70 | L3MBTL1 (0.46) | ALDH1A1TSHRLMNAPKMKDM4E | |
| SCHEMBL9733299 | 0.70 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |