Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733575 | 0.83 | ABCC9 (0.37) | BACE1LMNA | |
| SCHEMBL9733666 | 0.79 | ALDH1A1 (0.38) | ALDH1A1POLBTSHRSLC6A2SLC6A4 | |
| SCHEMBL9733240 | 0.76 | CYP11B2 (0.35) | ALDH1A1POLBTSHROPRM1OPRD1 | |
| SCHEMBL9740635 | 0.71 | IDO1 (0.35) | SMN1; SMN2 | |
| SCHEMBL9736930 | 0.70 | MEN1 (0.32) | ALDH1A1MAPTKMT2ABACE1MEN1 | |
| SCHEMBL9589012 | 0.69 | ALDH1A1 (0.36) | ALDH1A1POLBTSHRSLC6A2SLC6A4 | |
| SCHEMBL9733605 | 0.68 | FAAH (0.37) | ALDH1A1POLBTSHRPARP1TDP1 | |
| SCHEMBL9143344 | 0.68 | ABCC9 (0.45) | ALDH1A1TSHRMAPTKMT2ALMNA | |
| SCHEMBL9143340 | 0.68 | ABCC9 (0.45) | ALDH1A1TSHRMAPTKMT2ALMNA | |
| SCHEMBL9143349 | 0.68 | ABCC9 (0.45) | ALDH1A1TSHRMAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132307-A | TETRALIN COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-21 | — | — | US | disclosed |