Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326205 | 1.00 | PRKCA (0.32) | PRKCACES2ELANE | |
| SCHEMBL9803456 | 0.78 | GLS2 (0.34) | — | |
| SCHEMBL9326199 | 0.77 | PRKCA (0.46) | PRKCAELANE | |
| SCHEMBL9736017 | 0.74 | MAPT (0.47) | PRKCAELANE | |
| SCHEMBL8985096 | 0.74 | SIGMAR1 (0.34) | — | |
| SCHEMBL7294186 | 0.73 | TRPV1 (0.35) | — | |
| SCHEMBL8985104 | 0.73 | LMNA (0.36) | PRKCAELANE | |
| SCHEMBL9326797 | 0.72 | ASAH1 (0.44) | — | |
| SCHEMBL9128899 | 0.72 | LMNA (0.38) | PRKCAELANE | |
| SCHEMBL9326237 | 0.72 | ASAH1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0372941-A2 | Anti-inflammatory 5-hydroxy-2-furanones | ALLERGAN, INC (US) | 1990-06-13 | — | — | EP | disclosed |