Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738453 | 0.86 | LMNA (0.33) | — | |
| SCHEMBL9736242 | 0.86 | ABCB1 (0.38) | — | |
| SCHEMBL9736733 | 0.80 | IDO1 (0.34) | IDO1 | |
| SCHEMBL9735545 | 0.80 | — | — | |
| SCHEMBL9735702 | 0.78 | PBRM1 (0.31) | IDO1 | |
| SCHEMBL9737313 | 0.76 | PKM (0.31) | — | |
| SCHEMBL9735711 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL8084949 | 0.71 | ABCB1 (0.40) | — | |
| SCHEMBL9740635 | 0.69 | IDO1 (0.35) | IDO1 | |
| SCHEMBL9735602 | 0.68 | ABCC9 (0.41) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0415065-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |