Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737283 | 0.89 | PTGDR2 (0.47) | PTGS2MYCALDH1A1RAB9APTGDR2 | |
| SCHEMBL9738233 | 0.89 | KCNQ3 (0.43) | PTGS2MYCNTRK1PIM1KCNQ3 | |
| SCHEMBL9738192 | 0.88 | KDM4E (0.39) | PTGS2SMN1; SMN2NTRK1PIM1ALDH1A1 | |
| SCHEMBL9737572 | 0.86 | TSPO (0.45) | PTGS2MYCKCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL9737185 | 0.86 | KCNQ3 (0.41) | PTGS2MYCKCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL9737163 | 0.85 | ALDH1A1 (0.43) | PTGS2MYCSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9738542 | 0.83 | TSPO (0.44) | NPSR1 | |
| SCHEMBL9737222 | 0.82 | MYC (0.39) | PTGS2MYCKCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL9737699 | 0.78 | PTGDR2 (0.46) | PTGS2KCNQ3KCNQ2ALDH1A1L3MBTL1 | |
| SCHEMBL9737634 | 0.77 | KDM4E (0.48) | SMN1; SMN2ALDH1A1L3MBTL1PTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |