Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP7 | P09237 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134108 | 0.81 | LMNA (0.44) | ALDH1A1GAA | |
| SCHEMBL8697053 | 0.80 | ENPP3 (0.35) | MMP2MMP7MMP9MMP14MMP1 | |
| SCHEMBL10589667 | 0.79 | MAPT (0.34) | ALPLALPIALDH1A1FLT1FLT4 | |
| SCHEMBL9325335 | 0.74 | ALDH1A1 (0.47) | ALPLALPIALDH1A1FLT1FLT4 | |
| SCHEMBL8700100 | 0.74 | TSHR (0.50) | ALPLALPIALDH1A1FLT1FLT4 | |
| SCHEMBL10191441 | 0.73 | CES2 (0.44) | ALDH1A1 | |
| SCHEMBL10192440 | 0.71 | MAPK1 (0.46) | ALDH1A1FLT1FLT4KDRKDM4E | |
| SCHEMBL9323642 | 0.69 | ENPP3 (0.41) | MMP2MMP7MMP9MMP14MMP1 | |
| SCHEMBL1860425 | 0.69 | HPD (0.58) | ENPP3ENPP1 | |
| SCHEMBL30177033 | 0.69 | HPD (0.58) | ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089046-A | Herbicides or miticide | SANDOZ LTD. (CH) | 1992-02-18 | — | — | US | disclosed |
| EP-0336898-A2 | Substituted aryl or heteroaryl diones | SANDOZ AG (CH) | 1989-10-11 | — | — | EP | disclosed |