SCHEMBL9741815

SCHEMBL9741815

CC(=O)On1nc2cccc(-c3cccc(C)c3)c2n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA2 P47869 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CNR2 P34972 1/20 0.36
PIN1 Q13526 1/20 0.36
ENPP1 P22413 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SYK P43405 1/20 0.35
JMJD6 Q6NYC1 1/20 0.35
HTT P42858 2/20 0.35
KDM4E B2RXH2 2/20 0.35
USP2 O75604 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1643503 0.76 ENPP1 (0.41) KMT2AALDH1A1LMNANPC1RAB9A
SCHEMBL15499013 0.65 TGFBR1 (0.46) KMT2AALDH1A1RAB9AENPP1KDM4E
SCHEMBL3364407 0.65 HSD17B10 (0.44) KMT2AALDH1A1SMN1; SMN2GABRG2GABRB3
SCHEMBL3365166 0.65 GABRG2 (0.42) KMT2AGABRG2GABRB3GABRA2CNR2
SCHEMBL4785142 0.64 CHEK1 (0.47) KMT2AALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL8428274 0.63 PDE4D (0.35) KMT2A
SCHEMBL28414965 0.62 ACHE (0.55) KMT2AALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL28096983 0.62 NPC1 (0.36) KMT2AALDH1A1LMNANPC1RAB9A
SCHEMBL16248157 0.62 KDM4E (0.59) KMT2AALDH1A1LMNAL3MBTL1CNR2
SCHEMBL8645604 0.61 COMT (0.39) KMT2AALDH1A1LMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141990-A Protected phenyl benzotriazole uv rad absorber CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-08-25 US disclosed