SCHEMBL975060

SCHEMBL975060

Cn1c2cc[c]cc2c2c[c]ccc21

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.44
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
HSD17B10 Q99714 2/20 0.31
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193899 0.89 GPR3 (0.64) GPR3KDM4EALDH1A1MAPTHPGD
SCHEMBL4130418 0.83 KDM4E (0.42) KDM4EMAPT
SCHEMBL1419052 0.81 MAPT (0.41) GPR3KDM4EALDH1A1MAPTHPGD
SCHEMBL975434 0.80 GPR3 (0.44) GPR3KDM4EALDH1A1MAPTHPGD
SCHEMBL973904 0.76 HPGD (0.40) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL194516 0.76 GPR3 (0.64) GPR3KDM4EALDH1A1MAPTHPGD
SCHEMBL975523 0.75 ALDH1A1 (0.44) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL9145838 0.73 ALOX5 (0.53) KDM4EALDH1A1HSD17B10MEN1KMT2A
SCHEMBL3483473 0.73 KDM4E (0.33) GPR3KDM4EALDH1A1HPGDHSD17B10
SCHEMBL974629 0.73 PGR (0.44) KDM4EALDH1A1HPGDHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475937-B2 Silicone composition and organic light-emitting diode DOW CORNING CORPORATION (US) 2013-07-02 US disclosed
EP-2262861-B1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING (US) 2012-09-19 EP disclosed
US-20110017986-A1 Silicone Composition and Organic Light-Emitting Diode DOW CORNING CORPORATION 2011-01-27 US disclosed
EP-2262861-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE Dow Corning Corporation (US) 2010-12-22 EP disclosed
WO-2009120434-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING CORPORATION (US) 2009-10-01 WO disclosed