Sugi Predict

Sugi Predict / Compounds / SCHEMBL193899

SCHEMBL193899

SCHEMBL193899

Cn1c2cc[c]cc2c2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR3 P46089 1/20 0.64
▸ KDM4E B2RXH2 6/20 0.44
▸ MAPT P10636 5/20 0.44
▸ ALDH1A1 P00352 3/20 0.44
▸ HPGD P15428 3/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ HTT P42858 2/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ ALKBH5 Q6P6C2 1/20 0.44
▸ FTO Q9C0B1 1/20 0.44
▸ KIF11 P52732 1/20 0.43
▸ BCHE P06276 4/20 0.40
▸ ACHE P22303 4/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ PABPC1 P11940 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL975060 0.89 GPR3 (0.44) GPR3KDM4EMAPTALDH1A1HPGD
SCHEMBL194516 0.88 GPR3 (0.64) GPR3KDM4EMAPTALDH1A1HPGD
SCHEMBL29461528 0.80 GPR3 (1.00) GPR3KDM4EMAPTALDH1A1HPGD
SCHEMBL29321 0.80 GPR3 (1.00) GPR3KDM4EMAPTALDH1A1HPGD
SCHEMBL334753 0.79 ALDH1A1 (0.55) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL11142970 0.78 PGR (0.56) KDM4EALDH1A1HPGDL3MBTL1ACHE
Hydrochloric Acid SCHEMBL31174327 0.78 GPR3 (0.94) GPR3KDM4EMAPTALDH1A1HPGD
SCHEMBL18381839 0.78 GPR3 (0.94) GPR3KDM4EMAPTALDH1A1HPGD
Benzene SCHEMBL28231297 0.78 GPR3 (0.94) GPR3KDM4EMAPTALDH1A1HPGD
SCHEMBL1053368 0.77 L3MBTL1 (0.67) KDM4EMAPTALDH1A1HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230413661-A1 LUMINESCENT GOLD(III) COMPOUNDS WITH THERMALLY STIMULATED DELAYED PHOSPHORESCENCE (TSDP) PROPERTY FOR ORGANIC LIGHT-EMITTING DEVICES AND THEIR PREPARATION THE UNIVERSITY OF HONG KONG (CN) 2023-12-21 — — US claimed
US-20230052586-A1 DISUBSTITUTED ALKYNE DERIVATIVES MERCK PATENT GMBH (DE) 2023-02-16 — — US claimed
EP-3898588-B1 DISUBSTITUTED ALKYNE DERIVATIVES MERCK PATENT GMBH (DE) 2023-01-11 — — EP claimed
WO-2021249969-A1 COMBINATION PRODUCT FOR THE TREATMENT OF CANCER DISEASES MERCK PATENT GMBH (DE) 2021-12-16 — — WO claimed
EP-3898588-A1 DISUBSTITUTED ALKYNE DERIVATIVES Merck Patent GmbH (DE) 2021-10-27 — — EP claimed
WO-2020127960-A1 DISUBSTITUTED ALKYNE DERIVATIVES MERCK PATENT GMBH (DE) 2020-06-25 — — WO claimed
US-8962607-B2 Azetidinyl diamides as monoacylglycerol lipase inhibitors JANSSEN PHARMACEUTICA NV (BE) 2015-02-24 — — US claimed
EP-2421823-B1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2015-01-14 — — EP claimed
US-20140243305-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS JANSSEN PHARMACEUTICA NV (US) 2014-08-28 — — US claimed
US-8652752-B2 Sulphonium salt initiators BASF SE (DE) 2014-02-18 — — US claimed
US-20110166132-A1 Gamma Secretase Modulators AMGEN INC. (US) 2011-07-07 — — US claimed
US-20110015170-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2011-01-20 — — US claimed
US-20100324012-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2010-12-23 — — US claimed
US-20100297540-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-11-25 — — US claimed
WO-2010124114-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2010-10-28 — — WO claimed
WO-2010124086-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2010-10-28 — — WO claimed
EP-2231602-A1 GAMMA SECRETASE MODULATORS Amgen, Inc (US) 2010-09-29 — — EP claimed
EP-2197869-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-06-23 — — EP claimed
WO-2009075874-A1 GAMMA SECRETASE MODULATORS AMGEN INC. (US) 2009-06-18 — — WO claimed
WO-2009047105-A1 SULPHONIUM SALT INITIATORS BASF SE (CH) 2009-04-16 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230413661-A1 LUMINESCENT GOLD(III) COMPOUNDS WITH THERMALLY STIMULATED DELAYED PHOSPHORESCENCE (TSDP) PROPERTY FOR ORGANIC LIGHT-EMITTING DEVICES AND THEIR PREPARATION OCIAD1, OCIAD2, OSGEP GPR3 97/4885KDM4E 4380/4885MAPT 115/4885
US-20110015170-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS PNLIP, LPL, LIPA GPR3 2040/4885KDM4E 1931/4885MAPT 4519/4885
US-20140243305-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS PNLIP, LPL, LIPA GPR3 2040/4885KDM4E 1931/4885MAPT 4519/4885
US-20100297540-A1 SULPHONIUM SALT INITIATORS SULT1A1, SULT2A1, NCOA1 GPR3 1378/4885KDM4E 3933/4885MAPT 1627/4885
US-20110166132-A1 Gamma Secretase Modulators BACE1, BACE2, PSEN1 GPR3 1690/4885KDM4E 2860/4885MAPT 173/4885
US-20230052586-A1 DISUBSTITUTED ALKYNE DERIVATIVES BRCA1, MYC, PCNA GPR3 3424/4885KDM4E 2366/4885MAPT 3982/4885
US-20100324012-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS PNLIP, LPL, LIPA GPR3 2040/4885KDM4E 1931/4885MAPT 4519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.