5-Aminovaleric Acid

5-Aminovaleric Acid

SCHEMBL9751735

NCCCCC(=O)[O-].[K+]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of 5-Aminovaleric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminocaproic Acid SCHEMBL9128426 0.97 LMNA (0.56)
Potassium Ion SCHEMBL11126518 0.97 LMNA (0.56)
5-Aminovaleric Acid SCHEMBL9058910 0.94 NFKB1 (0.55)
5-Aminovaleric Acid SCHEMBL9129404 0.94
Aminocaproic Acid SCHEMBL11121733 0.92 LMNA (0.56)
Aminocaproic Acid SCHEMBL4956953 0.92 LMNA (0.56)
SCHEMBL11123518 0.92 LMNA (0.56)
SCHEMBL8107615 0.92 LMNA (0.56)
SCHEMBL17290449 0.92 LMNA (0.56)
Aminocaproic Acid SCHEMBL4608459 0.92 LMNA (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0445214-A4 CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE 1991-11-13 EP disclosed
EP-0445214-A1 CATALYTIC AND REACTIVE ANTIBODIES AND ANTIBODY FRAGMENTS AND METHODS FOR THEIR PREPARATION AND USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1991-09-11 EP disclosed
WO-1990005746-A1 CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1990-05-31 WO disclosed
EP-0039508-B1 A PROCESS FOR PREPARING ALKALI METAL AMINO ALKANOATES AND USE OF SAME PHILLIPS PETROLEUM COMPANY (US) 1984-03-07 EP disclosed
US-4324886-A POLYMERIZATION OF POLYHALO AROMATIC COMPOUND AND HYDROGEN SULFIDE PHILLIPS PETROLEUM COMPANY (US) 1982-04-13 US disclosed
EP-0039508-A1 A process for preparing alkali metal amino alkanoates and use of same PHILLIPS PETROLEUM COMPANY (US) 1981-11-11 EP disclosed