Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 5-Aminovaleric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341121 | 0.97 | LMNA (0.56) | — | |
| SCHEMBL30758644 | 0.97 | LMNA (0.56) | — | |
| SCHEMBL30279462 | 0.97 | LMNA (0.56) | — | |
| SCHEMBL8107615 | 0.97 | LMNA (0.56) | — | |
| Aminocaproic Acid SCHEMBL4608459 | 0.97 | LMNA (0.56) | — | |
| 5-Aminovaleric Acid SCHEMBL9751735 | 0.94 | — | — | |
| 5-Aminovaleric Acid SCHEMBL9058910 | 0.94 | NFKB1 (0.55) | — | |
| Potassium Ion SCHEMBL11126518 | 0.92 | LMNA (0.56) | — | |
| SCHEMBL11123518 | 0.92 | LMNA (0.56) | — | |
| SCHEMBL17290449 | 0.92 | LMNA (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115591585-B | Organic aluminum-SiO 2 Aerogel-like catalyst and preparation method thereof | 贵州大学 | 2023-09-19 | — | — | CN | claimed |
| CN-118895321-A | Enzymatic production of 2-oxo-1, 5-glutaric acid and separation and purification method thereof | 浙江仲兴生物医药科技有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115624988-B | Organic iron-SiO 2 Aerogel-like catalyst and preparation method thereof | 贵州大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-115591585-B | Organic aluminum-SiO 2 Aerogel-like catalyst and preparation method thereof | 贵州大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-115591585-B | Organic aluminum-SiO 2 Aerogel-like catalyst and preparation method thereof | 贵州大学 | 2023-09-19 | — | — | CN | disclosed |
| EP-3510041-B1 | PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-05-31 | — | — | EP | disclosed |
| US-5438115-A | Atleast one base as a reactant contacted with polymerization reaction mixture incremently during polymerization | PHILLIPS PETROLEUM COMPANY (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0534359-A1 | Process for preparing arylene sulfide polymers | PHILLIPS PETROLEUM COMPANY (US) | 1993-03-31 | — | — | EP | disclosed |
| US-5110902-A | High molecular weight polythioether-sulfones | PHILLIPS PETROLEUM COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5086163-A | High molecular weight polymers formed by contacting dihaloaromatic sulfone with complex of alkali metal aminoalkanoate and alkalimetal hydrosulfide | PHILLIPS PETROLEUM COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
| US-5023315-A | Reacting dihaloaromatic component with complex of lactams, alkali hydroxide and sulfur source, such as alkali metal bisulfide, thiolactam or hydrogen sulfide; whiteness, purity | PHILLIPS PETEROLEUM COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| US-5015725-A | Heat resistant thermoplastic resins for electrical components, aircraft or automobile parts, protective coatings | PHILLIPS PETROLEUM COMPANY (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0309955-A1 | Aromatic sulfide/sulfone polymer production | PHILLIPS PETROLEUM COMPANY (US) | 1989-04-05 | — | — | EP | disclosed |
| US-4370470-A | Multistage, agitated contactor and its use in continuous production of arylene sulfide polymer | PHILLIPS PETROLEUM COMPANY (US) | 1983-01-25 | — | — | US | disclosed |