Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IL1RN | P18510 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332099 | 0.82 | LNPEP (0.37) | LNPEPERAP2ERAP1CA2CA5A | |
| SCHEMBL7322813 | 0.76 | CTSD (0.37) | CA2CA5ACTSD | |
| SCHEMBL7324031 | 0.75 | CASP1 (0.38) | CTSDALDH1A1CPB2 | |
| SCHEMBL9754438 | 0.73 | ALOX5 (0.32) | CA2CA5AALDH1A1MAPT | |
| SCHEMBL9296616 | 0.72 | CA2 (0.34) | LNPEPERAP2ERAP1CA2CA5A | |
| SCHEMBL7270142 | 0.70 | CYP2D6 (0.51) | ERAP2ERAP1CA2CA5AIL1RN | |
| SCHEMBL7270146 | 0.70 | CYP2D6 (0.51) | ERAP2ERAP1CA2CA5AIL1RN | |
| SCHEMBL7327734 | 0.68 | ALOX5 (0.32) | CA2CA5AALDH1A1MAPT | |
| SCHEMBL10954138 | 0.68 | ACE (0.45) | — | |
| SCHEMBL10953109 | 0.68 | LGMN (0.41) | CTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015121-A1 | METHOD FOR TREATING FUNGAL INFECTION | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-17 | — | — | WO | disclosed |