Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756889 | 0.83 | LMNA (0.42) | GAAALDH1A1L3MBTL1PRKAB2PRKAG1 | |
| SCHEMBL13715916 | 0.81 | GAA (0.55) | GAAALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL9756896 | 0.80 | CES2 (0.38) | HPGDRAB9A | |
| SCHEMBL9756827 | 0.77 | ALDH1A1 (0.41) | GAAALDH1A1KDM4EHTTMAPK1 | |
| SCHEMBL9756855 | 0.75 | CES2 (0.41) | ALDH1A1NAPRTHTTL3MBTL1MAPK1 | |
| SCHEMBL9756986 | 0.74 | RAB9A (0.39) | GAAALDH1A1KDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL1123809 | 0.74 | RXFP1 (0.35) | GAAALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL9756998 | 0.73 | KMT2A (0.40) | GAAALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL13715636 | 0.73 | MDM2 (0.63) | ALDH1A1KDM4EHTTL3MBTL1MDM2 | |
| SCHEMBL12892192 | 0.72 | KDM4E (0.46) | GAAKDM4EHTTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | claimed |
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |