Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130672 | 0.83 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2CYP1A2LMNA | |
| SCHEMBL9756984 | 0.74 | GAA (0.38) | RAB9ASMN1; SMN2CYP1A2GAATP53 | |
| SCHEMBL9756855 | 0.74 | CES2 (0.41) | RAB9ANPC1SMN1; SMN2LMNAPKM | |
| SCHEMBL13715610 | 0.73 | SMN1; SMN2 (0.40) | RAB9ANPC1SMN1; SMN2CYP1A2LMNA | |
| SCHEMBL9756827 | 0.73 | ALDH1A1 (0.41) | RAB9ANPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL9756889 | 0.73 | LMNA (0.42) | RAB9ANPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL9756856 | 0.72 | PTPN1 (0.40) | SMN1; SMN2PTPN1PTPN11ALDH1A1 | |
| SCHEMBL9756896 | 0.70 | CES2 (0.38) | RAB9ANPC1CES2CES1 | |
| SCHEMBL9756903 | 0.70 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL1123809 | 0.70 | RXFP1 (0.35) | LMNAPOLBGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | claimed |
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |