Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10934234 | 0.84 | HDAC6 (0.50) | CES2CES1LMNAL3MBTL1NAPRT | |
| SCHEMBL10935204 | 0.82 | CA1 (0.49) | CES2CES1LMNAL3MBTL1NAPRT | |
| SCHEMBL10935199 | 0.82 | CA1 (0.49) | CES2CES1LMNAL3MBTL1NAPRT | |
| SCHEMBL9756903 | 0.79 | RAB9A (0.44) | L3MBTL1ALDH1A1HDAC8NPC1RAB9A | |
| SCHEMBL9756827 | 0.77 | ALDH1A1 (0.41) | CES2CES1LMNAALDH1A1HDAC1 | |
| SCHEMBL9756856 | 0.76 | PTPN1 (0.40) | ALDH1A1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL9756984 | 0.75 | GAA (0.38) | L3MBTL1NAPRTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL13715632 | 0.75 | NPC1 (0.58) | LMNANPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL9756986 | 0.74 | RAB9A (0.39) | CES2CES1LMNAALDH1A1NPC1 | |
| SCHEMBL9756889 | 0.74 | LMNA (0.42) | LMNAL3MBTL1ALDH1A1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | claimed |
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |