Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138103 | 0.83 | ALDH1A1 (0.56) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9756998 | 0.80 | KMT2A (0.40) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9756984 | 0.77 | GAA (0.38) | ALDH1A1RAB9ASMN1; SMN2KDM4EKMT2A | |
| SCHEMBL9756855 | 0.77 | CES2 (0.41) | ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9756896 | 0.76 | CES2 (0.38) | RAB9ANPC1HDAC1CES2CES1 | |
| SCHEMBL13715730 | 0.73 | NPC1 (0.54) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9756889 | 0.73 | LMNA (0.42) | ALDH1A1RAB9ANPC1SMN1; SMN2TDP1 | |
| SCHEMBL9756986 | 0.73 | RAB9A (0.39) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9756903 | 0.73 | RAB9A (0.44) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL5226512 | 0.72 | MMP1 (0.40) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | claimed |