Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11435965 | 0.94 | — | — | |
| SCHEMBL11262519 | 0.71 | — | — | |
| SCHEMBL10668659 | 0.69 | NOS1 (0.40) | — | |
| SCHEMBL6967129 | 0.67 | — | — | |
| SCHEMBL8233830 | 0.67 | — | — | |
| SCHEMBL1424226 | 0.65 | — | — | |
| SCHEMBL10668663 | 0.65 | — | — | |
| SCHEMBL27045625 | 0.65 | NOS1 (0.36) | — | |
| SCHEMBL19514785 | 0.65 | — | — | |
| SCHEMBL6967125 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255307-B1 | PROCESS FOR THE SYNTHESIS OF PENEMS | PFIZER INC. (US) | 1991-12-04 | — | — | EP | disclosed |
| EP-0249358-B1 | PROCESS FOR PENEM DERIVATIVES | PFIZER INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4782145-A | Process for penem derivatives | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0255307-A1 | Process for the synthesis of penems | PFIZER INC. (US) | 1988-02-03 | — | — | EP | disclosed |
| EP-0249358-A1 | Process for penem derivatives | PFIZER INC. (US) | 1987-12-16 | — | — | EP | disclosed |
| US-4351945-A | Two-phase process for the preparation of azole and azoline disulfides | EXXON RESEARCH & ENGINEERING CO. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4303539-A | OR FUEL ADDITIVES COMPRISING A POLYISOBUTENYL ISOTHIOCYANATE | EXXON RESEARCH & ENGINEERING CO. (US) | 1981-12-01 | — | — | US | disclosed |
| US-4286096-A | COUPLING OF AN ALKALI OR ALKALINE METAL SALT OF A THIOL-SUBSTITUTED FIVE-MEMBERED N-HETEROCYCLIC RING, SULFUR CHLORIDE, AND AN OLEFIN; CORROSION AND WEAR RESISTANCE; LUBRICANTS | EXXON RESEARCH & ENGINEERING CO. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4155910-A | OXIDATIVE COUPLING | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-05-22 | — | — | US | disclosed |
| US-4039552-A | CORROSION INHIBITION, WEAR RESISTANCE | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1977-08-02 | — | — | US | disclosed |