Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384831 | 0.81 | CYP1A2 (0.44) | ADRA2AADRA2BMLYCDALDH1A1MAPT | |
| SCHEMBL727319 | 0.79 | ALDH1A1 (0.49) | MLYCDALDH1A1MAPTHPGDTSHR | |
| SCHEMBL2402208 | 0.78 | L3MBTL1 (0.47) | MLYCDALDH1A1MAPTHPGDNOTUM | |
| SCHEMBL82487 | 0.76 | HPGD (0.61) | ADRA2AADRA2BADRA2CALDH1A1MAPT | |
| SCHEMBL15722856 | 0.76 | RAB9A (0.53) | ADRA2AADRA2BADRA2CALDH1A1MAPT | |
| SCHEMBL11896821 | 0.76 | ADRB2 (0.35) | MLYCDNOTUML3MBTL1GAA | |
| SCHEMBL8350993 | 0.74 | MAPT (0.54) | ADRA2AADRA2BADRA2CALDH1A1MAPT | |
| SCHEMBL1784560 | 0.74 | ALDH1A1 (0.52) | ADRA2AADRA2BADRA2CALDH1A1MAPT | |
| SCHEMBL11800833 | 0.74 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CALDH1A1MAPT | |
| SCHEMBL2703464 | 0.74 | OPRM1 (0.34) | MLYCDALDH1A1MAPTHPGDHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |