SCHEMBL976725

SCHEMBL976725

COC(=O)c1ccc2c(C)c3ccccc3c(C)c2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.59
PARP1 P09874 1/20 0.55
TSHR P16473 1/20 0.52
RAB9A P51151 3/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
GPR84 Q9NQS5 1/20 0.50
XDH P47989 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
NPC1 O15118 1/20 0.50
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 4/20 0.49
HPGD P15428 3/20 0.49
HSD17B10 Q99714 3/20 0.49
LMNA P02545 2/20 0.49
LCK P06239 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26114924 0.83 LCK (0.55) KIF11PARP1TSHRRAB9ACA12
SCHEMBL30044523 0.81 KIF11 (0.58) KIF11PARP1TSHRRAB9ACA12
SCHEMBL27729823 0.81 KIF11 (0.58) KIF11PARP1TSHRRAB9ACA12
SCHEMBL609398 0.81 KIF11 (0.58) KIF11PARP1TSHRRAB9ACA12
SCHEMBL29780395 0.79 ALDH1A1 (0.59) KIF11RAB9ANPC1ALDH1A1KDM4E
SCHEMBL975343 0.79 ALDH1A1 (0.59) KIF11RAB9ANPC1ALDH1A1KDM4E
SCHEMBL978869 0.79 KDM4E (0.59) PARP1TSHRALDH1A1KDM4EHPGD
SCHEMBL2527811 0.79 KIF11 (0.56) KIF11PARP1TSHRCA12CA1
SCHEMBL7936413 0.79 KIF11 (0.55) KIF11PARP1TSHRCA12CA1
SCHEMBL10901105 0.78 KIF11 (0.55) KIF11PARP1TSHRRAB9ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260053393-A1 NEAR-IR GLUCOSE SENSORS PROFUSA INC (US) 2026-02-26 US disclosed
US-20250230174-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2025-07-17 US disclosed
US-12285250-B2 Near-IR glucose sensors PROFUSA, INC (US) 2025-04-29 US disclosed
US-20210101915-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2021-04-08 US disclosed
US-20210101915-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2021-04-08 US disclosed
US-10717751-B2 Near-IR glucose sensors PROFUSA, INC. (US) 2020-07-21 US disclosed
EP-3562952-A1 NEAR-IR GLUCOSE SENSORS Profusa, Inc. (US) 2019-11-06 EP disclosed
US-20190010170-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2019-01-10 US disclosed
WO-2018125913-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2018-07-05 WO disclosed
WO-2018125913-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2018-07-05 WO disclosed
US-20180179233-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2018-06-28 US disclosed
US-7873398-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2011-01-18 US disclosed
US-7524985-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2009-04-28 US disclosed
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-12-25 US disclosed
US-7450980-B2 Intracorporeal substance measuring assembly TERUMO KABUSHIKI KAISHA (JP) 2008-11-11 US disclosed
US-7388110-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-06-17 US disclosed
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-01-24 US disclosed
EP-1619229-B1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO CORP (JP) 2007-04-11 EP disclosed
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA 2006-01-26 US disclosed
EP-1619229-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2006-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230174-A1 NEAR-IR GLUCOSE SENSORS IRS1, INSR, SLC2A4 KIF11 2460/4885PARP1 3760/4885TSHR 890/4885
US-20210101915-A1 NEAR-IR GLUCOSE SENSORS IRS1, INSR, SLC2A4 KIF11 2460/4885PARP1 3760/4885TSHR 890/4885
US-20260053393-A1 NEAR-IR GLUCOSE SENSORS INSR, IRS1, SLC2A4 KIF11 3166/4885PARP1 3471/4885TSHR 162/4885
US-20190010170-A1 NEAR-IR GLUCOSE SENSORS IRS1, INSR, SLC2A4 KIF11 2460/4885PARP1 3760/4885TSHR 890/4885
US-20180179233-A1 NEAR-IR GLUCOSE SENSORS IRS1, INSR, SLC2A4 KIF11 2460/4885PARP1 3760/4885TSHR 890/4885
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 KIF11 4634/4885PARP1 2737/4885TSHR 2939/4885
US-12285250-B2 Near-IR glucose sensors IRS1, SLC2A4, GPR119 KIF11 2088/4885PARP1 3639/4885TSHR 1126/4885
US-10717751-B2 Near-IR glucose sensors IRS1, G6PD, SLC2A8 KIF11 4765/4885PARP1 2320/4885TSHR 1218/4885
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 KIF11 4648/4885PARP1 3236/4885TSHR 2530/4885
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 KIF11 4648/4885PARP1 3236/4885TSHR 2530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.