Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768406 | 0.94 | SMN1; SMN2 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL9768414 | 0.78 | ADRB2 (0.47) | MAPT | |
| SCHEMBL9768419 | 0.77 | MAOB (0.59) | ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL9768407 | 0.74 | RAD52 (0.46) | — | |
| SCHEMBL10669694 | 0.73 | CA12 (0.43) | — | |
| SCHEMBL9768425 | 0.72 | ADRB2 (0.46) | MAPT | |
| SCHEMBL10486594 | 0.72 | PKM (0.60) | L3MBTL1SMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL4578170 | 0.72 | USP2 (0.83) | L3MBTL1SMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL9768428 | 0.72 | ALDH1A1 (0.42) | L3MBTL1SMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL10670024 | 0.70 | KDM4E (0.51) | L3MBTL1ALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073553-A | Treatment or prevention of osteoporosis | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0370760-A2 | Benzofuro[3,2-c]quinoline compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1990-05-30 | — | — | EP | disclosed |