Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.39 |
| ▸ | MEN1 | O00255 | 10/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29533009 | 0.86 | MAPT (0.51) | KMT2AMEN1MAPTGAACYP1A2 | |
| SCHEMBL41561 | 0.85 | MEN1 (0.48) | KMT2AMEN1MAPTGAACYP1A2 | |
| SCHEMBL41562 | 0.85 | MEN1 (0.48) | KMT2AMEN1MAPTGAACYP1A2 | |
| SCHEMBL1461510 | 0.84 | MEN1 (0.50) | KMT2AMEN1MAPTGAACYP1A2 | |
| SCHEMBL473260 | 0.84 | MEN1 (0.47) | KMT2AMEN1MAPTGAACYP1A2 | |
| SCHEMBL1831128 | 0.83 | MEN1 (0.47) | KMT2AMEN1MAPTGAACYP1A2 | |
| SCHEMBL31255141 | 0.83 | MEN1 (0.48) | KMT2AMEN1MAPTGAACYP1A2 | |
| SCHEMBL30371753 | 0.79 | KMT2A (0.53) | KMT2AMEN1MAPTGAACYP1A2 | |
| SCHEMBL9821198 | 0.78 | MEN1 (0.42) | KMT2AMEN1MAPTGAACYP1A2 | |
| SCHEMBL9821189 | 0.78 | MEN1 (0.41) | KMT2AMEN1MAPTGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| EP-0156193-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING PROTOZOAL INFECTIONS WITH A NOVEL ANTIBIOTIC | AMERICAN CYANAMID COMPANY (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0195397-B1 | M-CYANOPHENETHANOLAMINES AS ANIMAL GROWTH PROMOTERS AND ANTILIPOGENIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1989-12-13 | — | — | EP | disclosed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0113397-B1 | ANTHELMINTIC GEL COMPOSITIONS AND A METHOD FOR THEIR PREPARATION AT AMBIENT TEMPERATURES | AMERICAN CYANAMID COMPANY (US) | 1989-04-19 | — | — | EP | disclosed |
| EP-0224001-A1 | Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |
| US-4650802-A | ANTICOCCIDIAL, VETERINARY MEDICINE | AMERICAN CYANAMID COMPANY (US) | 1987-03-17 | — | — | US | disclosed |
| US-4649143-A | ANTICOCCIDIAL AGENT | AMERICAN CYANAMID COMPANY (US) | 1987-03-10 | — | — | US | disclosed |
| US-4614746-A | 5-fluorobenzonitrile derivatives for increasing the lean meat to fat ratio and/or enhancing the growth rate of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0195397-A1 | m-Cyanophenethanolamines as animal growth promoters and antilipogenic agents | AMERICAN CYANAMID COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |
| EP-0195396-A1 | 5-Fluorobenzonitrile derivatives and pharmacologically acceptable acid addition salts thereof for increasing the lean meat to fat ratio, and/or enhancing the growth rate of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |
| EP-0156193-A2 | Compounds and compositions for treating protozoal infections with a novel antibiotic | AMERICAN CYANAMID COMPANY (US) | 1985-10-02 | — | — | EP | disclosed |
| US-4543358-A | Anthelmintic gel composition and a method for their preparation at ambient temperatures | AMERICAN CYANAMID COMPANY (US) | 1985-09-24 | — | — | US | disclosed |
| EP-0049731-B1 | ANTHELMINTIC IMIDAZO(2,1-B)THIAZOLE GEL COMPOSITIONS | AMERICAN CYANAMID COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |
| EP-0113397-A2 | Anthelmintic gel compositions and a method for their preparation at ambient temperatures | AMERICAN CYANAMID COMPANY (US) | 1984-07-18 | — | — | EP | disclosed |
| EP-0049731-A2 | Anthelmintic imidazo(2,1-b)thiazole gel compositions | AMERICAN CYANAMID COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |
| US-4287176-A | SUBZERO GELATION TEMPERATURE | AMERICAN CYANAMID CO. (US) | 1981-09-01 | — | — | US | disclosed |