Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41562 | 0.94 | MEN1 (0.48) | MAPTALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL41561 | 0.94 | MEN1 (0.48) | MAPTALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL1461510 | 0.93 | MEN1 (0.50) | MAPTALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL473260 | 0.93 | MEN1 (0.47) | MAPTALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL1831128 | 0.92 | MEN1 (0.47) | MAPTALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL31255141 | 0.92 | MEN1 (0.48) | MAPTALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL10623311 | 0.90 | MAPT (0.62) | MAPTALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL9821193 | 0.86 | KMT2A (0.39) | MAPTALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL28836944 | 0.83 | MEN1 (0.48) | MAPTALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL342266 | 0.83 | MAPT (0.75) | MAPTALDH1A1LMNANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547208-B1 | PROCESS FOR REMOVING THE COLOUR FROM PREVIOUSLY DYED KERATINOUS HAIR FIBRES | OREAL (FR) | 2026-05-27 | — | — | EP | disclosed |
| US-12636246-B2 | Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound | L'OREAL (FR) | 2026-05-26 | — | — | US | disclosed |
| CN-122094656-A | Method for dyeing hair keratin fibres, comprising the step of washing the hair keratin fibres with a particular composition and subsequently applying to the hair keratin fibres a particular dyeing composition | — | 2026-05-26 | — | — | CN | disclosed |
| WO-2026039882-A1 | METHODS FOR REDUCING COLOR FADING IN COLOR-TREATED HAIR | L'OREAL (FR) | 2026-02-26 | — | — | WO | disclosed |
| US-12533303-B2 | Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition | L'OREAL (FR) | 2026-01-27 | — | — | US | disclosed |
| US-20260007583-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2026-01-08 | — | — | US | disclosed |
| US-20250381107-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| US-20250381106-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| US-20250375361-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-11 | — | — | US | disclosed |
| EP-4452211-B1 | PROCESS FOR REMOVING MAKEUP FROM KERATIN FIBRES WHICH HAVE BEEN TREATED BEFOREHAND WITH A COMPOSITION COMPRISING A PHOTOCROSSLINKABLE POLYMER | OREAL (FR) | 2025-12-03 | — | — | EP | disclosed |
| EP-4017465-A1 | COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE OF FORMULA (I), AT LEAST ONE ALKOXYSILANE OF FORMULA (II), AT LEAST ONE NONAMINO SILICONE, AND OPTIONALLY PIGMENTS AND/OR DIRECT DYES | L'OREAL (FR) | 2022-06-29 | — | — | EP | disclosed |
| WO-2022129344-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING THIS COMPOSITION | L'OREAL (FR) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129343-A1 | PROCESS FOR LIGHTENING KERATIN FIBRES | L'OREAL (FR) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129347-A1 | COMPOSITION FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES AND PROCESS USING THIS COMPOSITION | L'OREAL (FR) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129346-A1 | COMPOSITION FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES AND PROCESS EMPLOYING THIS COMPOSITION | L'OREAL (FR) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129345-A1 | PROCESS FOR LIGHTENING KERATIN FIBRES | L'OREAL (FR) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129157-A1 | COMPOSITION COMPRISING AT LEAST ONE SILICONE OF FORMULA (I), AT LEAST ONE SILICONE OF FORMULA (II) AND AT LEAST ONE COLORING AGENT | L'OREAL (FR) | 2022-06-23 | — | — | WO | disclosed |
| US-20220183944-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING A DIRECT DYE AND AN ALIPHATIC AMMONIUM SALT, AND COMPOSITION COMPRISING SAME | L'OREAL (FR) | 2022-06-16 | — | — | US | disclosed |
| EP-3986366-A1 | COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE, AT LEAST ONE NON-AMINO SILICONE AND WATER, THE ALKOXYSILANE/NON-AMINO SILICONE MASS RATIO RANGING FROM 95/5 TO 5/95 | L'OREAL (FR) | 2022-04-27 | — | — | EP | disclosed |
| CN-114340588-A | Composition comprising at least one alkoxysilane of formula (I), at least one alkoxysilane of formula (II), at least one non-amino silicone and optionally a pigment and/or direct dye | 莱雅公司 | 2022-04-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12533303-B2 | Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition | KRT18, CA12, CA7 | MAPT 1375/4885ALDH1A1 1626/4885LMNA 1592/4885 |
| US-20250381106-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, VIM, MAP1LC3A | MAPT 126/4885ALDH1A1 730/4885LMNA 74/4885 |
| US-20260007583-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, F12, VIM | MAPT 1050/4885ALDH1A1 1427/4885LMNA 211/4885 |
| US-12636246-B2 | Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound | KRT18, CYC1, CYBA | MAPT 3102/4885ALDH1A1 197/4885LMNA 773/4885 |
| US-20250375361-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, VIM, MAP1LC3A | MAPT 122/4885ALDH1A1 900/4885LMNA 85/4885 |
| US-20220183944-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING A DIRECT DYE AND AN ALIPHATIC AMMONIUM SALT, AND COMPOSITION COMPRISING SAME | KRT18, MARK1, IK | MAPT 465/4885ALDH1A1 873/4885LMNA 1449/4885 |
| US-20250381107-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, VIM, MAP1LC3A | MAPT 122/4885ALDH1A1 739/4885LMNA 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.