Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823938 | 0.78 | PRMT3 (0.35) | HRH3ALDH1A1HRH4PKMACHE | |
| SCHEMBL9824895 | 0.75 | DRD2 (0.34) | PGR | |
| SCHEMBL9824823 | 0.75 | MEN1 (0.32) | PGR | |
| SCHEMBL9036766 | 0.73 | SIGMAR1 (0.40) | HRH3PGRHRH4TSHR | |
| SCHEMBL9824395 | 0.72 | MEN1 (0.34) | TSHR | |
| SCHEMBL9824611 | 0.71 | CHRM5 (0.48) | HRH3ACHESMN1; SMN2 | |
| SCHEMBL9824968 | 0.71 | CXCR4 (0.43) | HRH3ACHESMN1; SMN2KDM4E | |
| SCHEMBL27267877 | 0.71 | NOS3 (0.38) | HRH3NOS3NOS1NOS2HRH4 | |
| SCHEMBL9824712 | 0.70 | MEN1 (0.40) | ACHE | |
| SCHEMBL9824002 | 0.70 | OPRM1 (0.32) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273239-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4873236-A | BRADYCARDIAL AGENTS | DR. KARL THOMAE GMBH (DE) | 1989-10-10 | — | — | US | disclosed |