Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955123 | 0.72 | HPGD (0.50) | RAB9ASMN1; SMN2MAPTHPGDKDM4E | |
| SCHEMBL16201493 | 0.70 | GSK3B (0.45) | SMN1; SMN2MAPTKMT2ALMNA | |
| SCHEMBL7733929 | 0.68 | MAPT (0.66) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL3370944 | 0.67 | PTGS2 (0.56) | RAB9AMAOBMAPTKMT2ALMNA | |
| SCHEMBL9831218 | 0.67 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL9829168 | 0.67 | FYN (0.46) | NPC1RAB9ASMN1; SMN2MAPK1ADORA2A | |
| SCHEMBL8234368 | 0.65 | MAPT (0.59) | NPC1MAOBMAPTKMT2ALMNA | |
| SCHEMBL9320698 | 0.65 | LTA4H (0.50) | MAPTALDH1A1 | |
| SCHEMBL10858118 | 0.65 | LMNA (0.58) | NPC1RAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL2037881 | 0.65 | KMT2A (0.43) | RAB9AMAPTKMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233804-B1 | MONOARYL-5-AS TRIAZINONES SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | PIERRE FABRE MEDICAMENT (FR) | 1991-09-25 | — | — | EP | claimed |