Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834295 | 0.87 | NAAA (0.43) | NAAAGLSDAOTAAR1NR3C2 | |
| SCHEMBL9832110 | 0.86 | TDP1 (0.41) | NAAAGLSTDP1 | |
| SCHEMBL9833331 | 0.84 | HDAC1 (0.47) | HDAC1HDAC8TAAR1NR3C2 | |
| SCHEMBL9834514 | 0.80 | HRH1 (0.41) | NAAACES1NCEH1 | |
| SCHEMBL9833135 | 0.80 | CNR1 (0.40) | HDAC1HDAC6GLS | |
| SCHEMBL9832892 | 0.79 | NAAA (0.37) | NAAAGLS | |
| SCHEMBL9832722 | 0.76 | MPO (0.39) | HDAC1GLSDAOTAAR1NR3C2 | |
| SCHEMBL9832047 | 0.75 | HRH1 (0.45) | HDAC1HDAC6NAAAGLS | |
| SCHEMBL9833192 | 0.75 | ALDH1A1 (0.37) | HDAC1HDAC6HDAC2GLSTDP1 | |
| SCHEMBL765851 | 0.71 | MAPT (0.66) | HDAC1HDAC6HDAC3HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129846-B1 | (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES | AMERICAN CYANAMID COMPANY (US) | 1991-05-08 | — | — | EP | claimed |