SCHEMBL9832892

SCHEMBL9832892

Nc1n[nH]cc1CC(=O)CCCCCCCCCCCCCCc1ccc(F)cc1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.37
FAAH O00519 2/20 0.35
GLS O94925 1/20 0.35
MPO P05164 1/20 0.35
LMNA P02545 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9833181 0.88 HDAC3 (0.44) NAAA
SCHEMBL9832110 0.88 TDP1 (0.41) NAAAFAAHGLS
SCHEMBL9834514 0.86 HRH1 (0.41) NAAAFAAH
SCHEMBL9834295 0.86 NAAA (0.43) NAAAFAAHGLS
SCHEMBL9837576 0.86 ALOX5 (0.46) FAAH
SCHEMBL9834740 0.81 ALOX5 (0.44) GLS
SCHEMBL9833469 0.79 HDAC1 (0.46) NAAAGLS
SCHEMBL9833135 0.79 CNR1 (0.40) GLS
SCHEMBL9833192 0.76 ALDH1A1 (0.37) GLS
SCHEMBL9831944 0.76 SMN1; SMN2 (0.44) GLS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0129846-B1 (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES AMERICAN CYANAMID COMPANY (US) 1991-05-08 EP claimed