Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837576 | 0.88 | ALOX5 (0.46) | IGF1RALOX15FAAH | |
| SCHEMBL9833181 | 0.88 | HDAC3 (0.44) | NAAAIGF1RALOX15 | |
| SCHEMBL9832892 | 0.88 | NAAA (0.37) | NAAAGLSFAAH | |
| SCHEMBL9834514 | 0.86 | HRH1 (0.41) | NAAAFAAH | |
| SCHEMBL9833469 | 0.86 | HDAC1 (0.46) | TDP1NAAAGLS | |
| SCHEMBL9834740 | 0.83 | ALOX5 (0.44) | GLS | |
| SCHEMBL9833965 | 0.81 | NAAA (0.41) | NAAAFAAH | |
| SCHEMBL9833192 | 0.76 | ALDH1A1 (0.37) | TDP1GLSALOX15 | |
| SCHEMBL20330088 | 0.70 | NAAA (0.52) | TDP1L3MBTL1NAAAIGF1RALOX15 | |
| SCHEMBL25456072 | 0.70 | TDP1 (0.59) | TDP1L3MBTL1NAAAIGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129846-B1 | (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES | AMERICAN CYANAMID COMPANY (US) | 1991-05-08 | — | — | EP | claimed |