Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832104 | 0.78 | CHRM2 (0.40) | GAAKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL9831654 | 0.76 | MAPT (0.41) | METGAAKDM4EMAPTALOX5 | |
| SCHEMBL9834283 | 0.72 | OPRM1 (0.58) | GAAKDM4EMAPTALOX5PTGS1 | |
| SCHEMBL10423292 | 0.72 | KDM4E (0.41) | METGAAKDM4EMAPTALOX5 | |
| SCHEMBL9831337 | 0.69 | CHRM2 (0.42) | GAAKDM4EL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9832269 | 0.67 | MAPT (0.36) | GAAKDM4EMAPTALOX5PTGS1 | |
| SCHEMBL26853170 | 0.66 | TRPV1 (0.46) | METLMNATRPV1 | |
| SCHEMBL9832363 | 0.66 | OPRM1 (0.43) | MAPTPTGS2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9799289 | 0.65 | OPRM1 (0.43) | GAAKDM4EMAPTPTGS2L3MBTL1 | |
| SCHEMBL13851149 | 0.65 | MET (0.60) | METGAAKDM4EMAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297782-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-22 | — | — | EP | claimed |