Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833350 | 0.88 | TUBB4A (0.41) | CYP19A1 | |
| SCHEMBL9837576 | 0.85 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9832110 | 0.83 | TDP1 (0.41) | GLS | |
| SCHEMBL9833469 | 0.81 | HDAC1 (0.46) | GLSPPARGPPARA | |
| SCHEMBL9832892 | 0.81 | NAAA (0.37) | GLS | |
| SCHEMBL9833181 | 0.81 | HDAC3 (0.44) | PPARGPPARA | |
| SCHEMBL9834514 | 0.79 | HRH1 (0.41) | — | |
| SCHEMBL5192275 | 0.77 | KDM4E (0.57) | ALOX5CYP19A1EPHX2PPARGPPARA | |
| SCHEMBL2221405 | 0.75 | KDM4E (0.59) | ALOX5CYP19A1PPARGPPARA | |
| SCHEMBL7415347 | 0.73 | PPARA (0.58) | ALOX5EPHX2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129846-B1 | (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES | AMERICAN CYANAMID COMPANY (US) | 1991-05-08 | — | — | EP | claimed |