Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | SCNN1A | P37088 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832110 | 0.88 | TDP1 (0.41) | IGF1RALOX15FAAH | |
| SCHEMBL9833181 | 0.86 | HDAC3 (0.44) | LTB4RIGF1RALOX15 | |
| SCHEMBL9832892 | 0.86 | NAAA (0.37) | FAAH | |
| SCHEMBL9834740 | 0.85 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9834514 | 0.84 | HRH1 (0.41) | FAAH | |
| SCHEMBL9833469 | 0.80 | HDAC1 (0.46) | POLB | |
| SCHEMBL9833192 | 0.74 | ALDH1A1 (0.37) | ALOX5POLBALOX15 | |
| SCHEMBL933946 | 0.74 | ALOX5 (0.59) | ALOX5LTB4RF2RL1POLBCALM1 | |
| SCHEMBL13522667 | 0.74 | ALOX5 (0.59) | ALOX5LTB4RF2RL1POLBCALM1 | |
| SCHEMBL20019549 | 0.72 | ALOX5 (0.61) | ALOX5F2RL1POLBCALM1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129846-B1 | (3-AMINO-1H-PYRAZOL-4-YL)(ARYL)METHANONES | AMERICAN CYANAMID COMPANY (US) | 1991-05-08 | — | — | EP | claimed |