Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836562 | 0.86 | P2RX7 (0.36) | P2RX7KMT2AMAPTLMNA | |
| SCHEMBL9836237 | 0.82 | ALDH1A1 (0.41) | P2RX7MAPTLMNASMN1; SMN2 | |
| SCHEMBL9834568 | 0.80 | HSP90AA1 (0.38) | TBXAS1MAPK14 | |
| SCHEMBL9836786 | 0.78 | DRD2 (0.43) | TERTKMT2ASMN1; SMN2 | |
| SCHEMBL9836629 | 0.71 | CYP2C19 (0.41) | KMT2ATBXAS1LMNA | |
| SCHEMBL8797476 | 0.71 | MAPT (0.43) | P2RX7TERTKMT2AMAPTTBXAS1 | |
| SCHEMBL9834971 | 0.70 | ALDH1A1 (0.36) | KMT2ATBXAS1 | |
| SCHEMBL9836996 | 0.69 | MAOA (0.48) | P2RX7TERTMAPTMAPK14LMNA | |
| SCHEMBL9836548 | 0.68 | LMNA (0.35) | P2RX7TERTKMT2AMAPTMAPK14 | |
| SCHEMBL8797939 | 0.68 | LMNA (0.47) | KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129879-B1 | A [1] benzepino(3,4-b)pyridine derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-09-11 | — | — | EP | claimed |
| US-4547496-A | Antiulcer [1] benzepino[3,4-b]pyridine and compositions | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-10-15 | — | — | US | claimed |
| EP-0129879-A2 | A [1] benzepino(3,4-b)pyridine derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-01-02 | — | — | EP | claimed |
| JP-60078985-A | — | — | None | — | — | JP | disclosed |
| EP-0129879-B1 | A [1] benzepino(3,4-b)pyridine derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4547496-A | Antiulcer [1] benzepino[3,4-b]pyridine and compositions | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-10-15 | — | — | US | disclosed |
| JP-S6078985-A | NOVEL (1)BENZEPINO(3,4-B)PYRIDINE DERIVATIVE | KYOWA HAKKO KOGYO CO LTD | 1985-05-04 | — | — | JP | disclosed |