Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837059 | 0.80 | MEN1 (0.36) | TSHRMEN1USP2KMT2ASMN1; SMN2 | |
| SCHEMBL9836548 | 0.78 | LMNA (0.35) | P2RX7MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9836562 | 0.72 | P2RX7 (0.36) | MAPK1P2RX7GAAMEN1USP2 | |
| SCHEMBL9836747 | 0.70 | GAA (0.36) | TSHRHPGDMAPK1GAAHTT | |
| SCHEMBL9836996 | 0.69 | MAOA (0.48) | P2RX7CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8797476 | 0.69 | MAPT (0.43) | TSHRP2RX7MEN1KMT2ATBXAS1 | |
| SCHEMBL9834971 | 0.68 | ALDH1A1 (0.36) | MEN1KMT2ATBXAS1ALDH1A1ALOX15 | |
| SCHEMBL9836237 | 0.68 | ALDH1A1 (0.41) | P2RX7HTTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9835913 | 0.67 | P2RX7 (0.36) | P2RX7KMT2ATBXAS1LMNASMN1; SMN2 | |
| SCHEMBL9835639 | 0.67 | ALDH1A1 (0.42) | GAAALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129879-B1 | A [1] benzepino(3,4-b)pyridine derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-09-11 | — | — | EP | claimed |
| US-4547496-A | Antiulcer [1] benzepino[3,4-b]pyridine and compositions | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-10-15 | — | — | US | claimed |
| EP-0129879-A2 | A [1] benzepino(3,4-b)pyridine derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-01-02 | — | — | EP | claimed |