Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | DRD3 | P35462 | 6/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | HTR7 | P34969 | 4/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | DRD5 | P21918 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840193 | 0.87 | CASP3 (0.41) | SIGMAR1MAPTHRH3RAB9A | |
| SCHEMBL9698919 | 0.68 | TGFBR1 (0.44) | RAB9A | |
| SCHEMBL30928708 | 0.66 | NPC1 (0.35) | SIGMAR1HTR2AHRH3RAB9AHTR2B | |
| SCHEMBL1430472 | 0.64 | ALDH1A1 (0.59) | HTR2ASLC6A4HTR2CMAPTADRA2C | |
| SCHEMBL9010525 | 0.64 | FFAR1 (0.41) | HTR7MAPT | |
| SCHEMBL21410505 | 0.63 | P2RX7 (0.36) | — | |
| SCHEMBL2615717 | 0.63 | ESR1 (0.63) | HTR2ASLC6A4HTR2CADRA2C | |
| SCHEMBL9717309 | 0.63 | ESR1 (0.63) | HTR2ASLC6A4HTR2CADRA2C | |
| SCHEMBL13564082 | 0.63 | ESR1 (0.63) | HTR2ASLC6A4HTR2CADRA2C | |
| SCHEMBL3941872 | 0.63 | ESR1 (0.63) | HTR2ASLC6A4HTR2CADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002941-A | Antiarthritic agents, arachidonic acid metabolism | SMITHKLINE BEECHAM CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |