Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258359 | 0.79 | F9 (0.54) | CHEK2HSD17B10MAPTHRH2HRH1 | |
| SCHEMBL30963937 | 0.75 | RXRA (0.51) | CHEK2MAPTPRMT6RXRARXRB | |
| SCHEMBL28294058 | 0.75 | CHEK2 (0.53) | CHEK2USP2HSD17B10MEN1MAPT | |
| SCHEMBL9258332 | 0.74 | F9 (0.45) | CHEK2HSD17B10MAPTKMT2AHRH2 | |
| SCHEMBL5702207 | 0.72 | MGLL (0.53) | — | |
| SCHEMBL9256522 | 0.72 | PRMT6 (0.48) | CHEK2USP2KMT2APRMT6RXRA | |
| SCHEMBL9258419 | 0.71 | P2RX3 (0.44) | CHEK2PRMT6P2RX3HTR1ACNR1 | |
| SCHEMBL7871362 | 0.71 | KAT6A (0.48) | CHEK2USP2HSD17B10MEN1MAPT | |
| SCHEMBL9261099 | 0.70 | LMNA (0.53) | HSD17B10MEN1ALOX15KMT2ARXRA | |
| SCHEMBL5504603 | 0.70 | HDAC1 (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |