Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856849 | 0.83 | POLB (0.47) | DUTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9856644 | 0.82 | NPC1 (0.43) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL9856553 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL10351423 | 0.74 | TSHR (0.48) | ALDH1A1EPHX2KDM4ENPC1LMNA | |
| SCHEMBL10770087 | 0.73 | LTA4H (0.44) | ALDH1A1LMNATSHRMAPK1ADAMTS5 | |
| SCHEMBL11338090 | 0.73 | EPHX2 (0.49) | ALDH1A1EPHX2MEN1KMT2AHPGD | |
| SCHEMBL27406824 | 0.72 | EPHX2 (0.57) | ALDH1A1EPHX2MEN1KMT2AHPGD | |
| SCHEMBL562070 | 0.71 | KDM4E (0.49) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL27363608 | 0.71 | TSHR (0.43) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL7920783 | 0.70 | KEAP1 (0.48) | MEN1KMT2AMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240463-B1 | SUBSTITUTED AMINOOXYPROPION AMIDES | CIBA-GEIGY AG (CH) | 1990-11-22 | — | — | EP | claimed |
| US-4760179-A | Substituted aminoxy-propionamides | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | claimed |
| US-5057563-A | Oxidation, heat, radiation stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| US-4929657-A | STABILIZERS AGAINST OXIDATION, RADIATION FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4760179-A | Substituted aminoxy-propionamides | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |