Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DUT | P33316 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856644 | 0.87 | NPC1 (0.43) | HDAC1HDAC6CTSSCTSKMEN1 | |
| SCHEMBL9856843 | 0.83 | DUT (0.41) | DUTCTSSCTSKMEN1KMT2A | |
| SCHEMBL562070 | 0.75 | KDM4E (0.49) | POLBMEN1KMT2AKDM4EHTT | |
| SCHEMBL31117181 | 0.74 | POLB (0.60) | POLBHDAC6MEN1KMT2AMAPT | |
| SCHEMBL7920783 | 0.74 | KEAP1 (0.48) | HDAC1HDAC6MEN1KMT2AMAPT | |
| SCHEMBL561596 | 0.73 | KEAP1 (0.47) | HDAC1HDAC6MEN1KMT2AMAPT | |
| Potassium Ion SCHEMBL561597 | 0.70 | HDAC3 (0.46) | HDAC1HDAC6MEN1KMT2AL3MBTL1 | |
| SCHEMBL2238587 | 0.70 | ALOX5 (0.49) | POLBKMT2AL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL10352510 | 0.69 | TDP1 (0.46) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL562607 | 0.67 | RIPK1 (0.47) | MEN1KMT2AHTTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240463-B1 | SUBSTITUTED AMINOOXYPROPION AMIDES | CIBA-GEIGY AG (CH) | 1990-11-22 | — | — | EP | claimed |
| US-4760179-A | Substituted aminoxy-propionamides | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | claimed |
| US-5057563-A | Oxidation, heat, radiation stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| US-4929657-A | STABILIZERS AGAINST OXIDATION, RADIATION FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4760179-A | Substituted aminoxy-propionamides | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |