Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hexadecane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.46 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tridecane SCHEMBL27760718 | 1.00 | CA2 (0.46) | CA2CA1CPT2CPT1ACPT1B | |
| Dodecane SCHEMBL27642194 | 1.00 | CA2 (0.46) | CA2CA1CPT2CPT1ACPT1B | |
| Octane SCHEMBL28131914 | 1.00 | CA2 (0.46) | CA2CA1CPT2CPT1ACPT1B | |
| Hexadecane SCHEMBL9858214 | 1.00 | CA2 (0.46) | CA2CA1CPT2CPT1ACPT1B | |
| Decanol SCHEMBL28385705 | 0.95 | CA2 (0.42) | CA2CPT2CPT1ACPT1B | |
| SCHEMBL28773461 | 0.95 | CA2 (0.42) | CA2CPT2CPT1ACPT1B | |
| Myristyl Alcohol SCHEMBL28888229 | 0.95 | CA2 (0.42) | CA2CPT2CPT1ACPT1B | |
| Cetyl Alcohol SCHEMBL29005862 | 0.95 | CA2 (0.42) | CA2CPT2CPT1ACPT1B | |
| Tridecan-1-Ol SCHEMBL28562611 | 0.95 | CA2 (0.42) | CA2CPT2CPT1ACPT1B | |
| Tridecan-1-Ol SCHEMBL28032219 | 0.95 | CA2 (0.42) | CA2CPT2CPT1ACPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225948-B1 | DRY PIGMENT SYSTEM | CROMPTON & KNOWLES CORPORATION (US) | 1991-03-20 | — | — | EP | claimed |
| CN-115734806-A | Masked IL-12 cytokines and cleavage products thereof | 西里欧发展公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-115605504-A | Novel IL-21 prodrugs and methods of use thereof | 奥美药业有限公司（US） | 2023-01-13 | — | — | CN | disclosed |
| CN-114401997-A | Cytokine prodrugs and dual prodrugs | 奥美药业有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114222764-A | IL-2 fusion proteins that preferentially bind IL-2R alpha | 奥美药业有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-1021618-C | Herbicidal composition | NISSAN CHEMICAL IND LTD (JP) | 1993-07-21 | — | — | CN | disclosed |
| CN-87101907-A | HERBICIDAL COMPOSITION | — | 1988-10-12 | — | — | CN | disclosed |