Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR1F | P30939 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10745063 | 0.77 | DRD2 (0.32) | HCAR1 | |
| SCHEMBL9865854 | 0.76 | HCAR1 (0.39) | HTR1DHTR1BHTR1FHCAR1 | |
| SCHEMBL10744948 | 0.73 | HCAR1 (0.31) | HCAR1 | |
| SCHEMBL9545465 | 0.73 | LTB4R (0.30) | — | |
| SCHEMBL9545447 | 0.71 | — | — | |
| SCHEMBL10745662 | 0.70 | TXNRD1 (0.34) | HTR1DHTR1BHTR1FHCAR1 | |
| SCHEMBL7038679 | 0.70 | CCR1 (0.41) | HCAR1 | |
| SCHEMBL9867638 | 0.69 | FFAR4 (0.34) | HCAR1 | |
| SCHEMBL10461699 | 0.68 | PTGS2 (0.43) | HCAR1 | |
| SCHEMBL9867762 | 0.68 | ALDH1A1 (0.37) | HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |