Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865651 | 0.86 | HCAR1 (0.33) | ALDH1A1NFE2L2HCAR1 | |
| SCHEMBL9866531 | 0.84 | POLB (0.36) | ALDH1A1SMN1; SMN2NFE2L2HCAR1LMNA | |
| SCHEMBL10745662 | 0.81 | TXNRD1 (0.34) | NFE2L2HCAR1 | |
| SCHEMBL10373802 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL9866727 | 0.80 | NFE2L2 (0.34) | KDM4ENFE2L2HCAR1 | |
| SCHEMBL9867957 | 0.79 | MEN1 (0.33) | ALDH1A1SMN1; SMN2NFE2L2HCAR1 | |
| SCHEMBL9866719 | 0.78 | L3MBTL1 (0.38) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL9865854 | 0.77 | HCAR1 (0.39) | SMN1; SMN2HCAR1LMNA | |
| SCHEMBL9867057 | 0.77 | ALDH1A1 (0.35) | ALDH1A1KDM4EGAASMN1; SMN2NFE2L2 | |
| SCHEMBL9865677 | 0.77 | HCAR1 (0.36) | NFE2L2HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |