Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602809 | 0.88 | DRD2 (0.34) | HTR1AHRH3DRD2MAOBKCNH2 | |
| SCHEMBL9602555 | 0.86 | ALDH1A1 (0.34) | DRD2MAOB | |
| SCHEMBL9602330 | 0.85 | ESR1 (0.37) | HRH3DRD2ESR1ESR2 | |
| SCHEMBL9601947 | 0.82 | ADRB1 (0.39) | — | |
| SCHEMBL9603224 | 0.82 | DRD2 (0.36) | HTR1AHRH3DRD2KCNH2HTR2C | |
| SCHEMBL9602515 | 0.81 | ALDH1A1 (0.33) | ACHEDRD2 | |
| Fumaric Acid SCHEMBL9865911 | 0.81 | KDM4E (0.35) | DRD2 | |
| SCHEMBL9602850 | 0.79 | DRD2 (0.35) | HTR1ADRD2KCNH2ESR1 | |
| Hydrochloric Acid SCHEMBL9602310 | 0.79 | S1PR1 (0.33) | ACHEDRD2 | |
| Fumaric Acid SCHEMBL9602547 | 0.78 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |